PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33125572-3 2021 We also demonstrated that oridonin abrogated inflammation through inhibiting the phosphorylation of NF-kappaBp65 as well as its downstream gene (iNOS, COX-2, IL-1beta, and IL-6) level. oridonin 26-34 interleukin 1 alpha Homo sapiens 158-166 33463129-8 2020 Following the treatment of U937 cells with oridonin, the expression of Gal-9, TIM-3, and IL-1beta genes was down-regulated, and the Gal-9 secretion and NF-kB phosphorylation were diminished, whereas doxorubicin increased all of these factors. oridonin 43-51 interleukin 1 alpha Homo sapiens 89-97 31971852-5 2020 Treatment with oridonin for 24 h increased apoptosis by 4.1%, and increased the protein levels of Bax and cleaved caspase-3 but significantly decreased the levels of IL-1beta in the culture supernatant (p < 0.05). oridonin 15-23 interleukin 1 alpha Homo sapiens 166-174