PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33463129-8	2020	Following the treatment of U937 cells with oridonin, the expression of Gal-9, TIM-3, and IL-1beta genes was down-regulated, and the Gal-9 secretion and NF-kB phosphorylation were diminished, whereas doxorubicin increased all of these factors.	oridonin	43-51	interleukin 1 alpha	Homo sapiens	89-97	
31971852-5	2020	Treatment with oridonin for 24 h increased apoptosis by 4.1%, and increased the protein levels of Bax and cleaved caspase-3 but significantly decreased the levels of IL-1beta in the culture supernatant (p < 0.05).	oridonin	15-23	interleukin 1 alpha	Homo sapiens	166-174	
33125572-3	2021	We also demonstrated that oridonin abrogated inflammation through inhibiting the phosphorylation of NF-kappaBp65 as well as its downstream gene (iNOS, COX-2, IL-1beta, and IL-6) level.	oridonin	26-34	interleukin 1 alpha	Homo sapiens	158-166