PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26059423-0 2015 Protective efficacy of carnosic acid against hydrogen peroxide induced oxidative injury in HepG2 cells through the SIRT1 pathway. salvin 23-36 sirtuin 1 Homo sapiens 115-120 26845416-0 2016 Carnosic acid attenuates acute ethanol-induced liver injury via a SIRT1/p66Shc-mediated mitochondrial pathway. salvin 0-13 sirtuin 1 Homo sapiens 66-71 24557422-11 2014 Interestingly, the protective effect of carnosic acid and ischemic preconditioning was positively associated with sirtuin 1 activation. salvin 40-53 sirtuin 1 Homo sapiens 114-123 24557422-13 2014 Sirtuin 1 small interfering RNA knockdown experiments confirmed that carnosic acid increased sirtuin 1-mediated repression of p66shc in HepG2 cells and that the protective effect of carnosic acid against hypoxia/reoxygenation injury was inhibited by the sirtuin 1 inhibitor nicotinamide. salvin 69-82 sirtuin 1 Homo sapiens 0-9 24557422-13 2014 Sirtuin 1 small interfering RNA knockdown experiments confirmed that carnosic acid increased sirtuin 1-mediated repression of p66shc in HepG2 cells and that the protective effect of carnosic acid against hypoxia/reoxygenation injury was inhibited by the sirtuin 1 inhibitor nicotinamide. salvin 69-82 sirtuin 1 Homo sapiens 93-102 24557422-13 2014 Sirtuin 1 small interfering RNA knockdown experiments confirmed that carnosic acid increased sirtuin 1-mediated repression of p66shc in HepG2 cells and that the protective effect of carnosic acid against hypoxia/reoxygenation injury was inhibited by the sirtuin 1 inhibitor nicotinamide. salvin 69-82 sirtuin 1 Homo sapiens 254-263 24557422-13 2014 Sirtuin 1 small interfering RNA knockdown experiments confirmed that carnosic acid increased sirtuin 1-mediated repression of p66shc in HepG2 cells and that the protective effect of carnosic acid against hypoxia/reoxygenation injury was inhibited by the sirtuin 1 inhibitor nicotinamide. salvin 182-195 sirtuin 1 Homo sapiens 254-263 24557422-14 2014 These results suggest that carnosic acid protects hepatocytes from hypoxia/reoxygenation damage through sirtuin 1-mediated p66shc suppression. salvin 27-40 sirtuin 1 Homo sapiens 104-113