PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30227824-8	2019	Administration of Trolox, carnosic acid and HCG increased the number of healthy cells and decreased the expression of Caspase-3 and Bax, but significantly increased the expression of Bcl-2 compared to the ischemic group.	salvin	26-39	caspase 3	Homo sapiens	118-127	
25337586-6	2014	RESULTS: Carnosic acid induced sub-diploid DNA content, sub-G1, population and poly (ADP-ribose) polymerase (PARP) cleavage and activated caspase-3.	salvin	9-22	caspase 3	Homo sapiens	138-147	
28440400-7	2017	Caspase-3 signaling pathway was promoted in carnosic acid and fisetin co-treatment, which was accompanied by anti-apoptotic proteins of Bcl-2 and Bcl-xl decreasing and pro-apoptotic signals of Bax and Bad increasing.	salvin	44-57	caspase 3	Homo sapiens	0-9	
28282784-0	2017	Carnosic acid cooperates with tamoxifen to induce apoptosis associated with Caspase-3 activation in breast cancer cells in vitro and in vivo.	salvin	0-13	caspase 3	Homo sapiens	76-85	
28282784-6	2017	Caspase-3 signaling pathway was promoted for carnosic acid and tamoxifen co-treatment.	salvin	45-58	caspase 3	Homo sapiens	0-9	
29285102-10	2017	Furthermore, the apoptosis of H9c2 cardiomyocytes resulted from hypoxia/reoxygenation was inhibited by carnosic acid through the upregulation of Bcl-2 and the downregulation of Bax and caspase-3 levels.	salvin	103-116	caspase 3	Homo sapiens	185-194	
22531045-5	2012	Measuring cellular ATP, carnosic acid showed a dose-dependent increase in hepatotoxicity with an EC(50) value of 94.8 +- 36.7 muM in three human hepatocyte donors without a concurrent increase in the apoptosis markers caspase-3/7.	salvin	24-37	caspase 3	Homo sapiens	218-229	
20661831-5	2010	Early stage of curcumin/carnosic acid-induced apoptosis was associated with cleavage (activation) of caspase-8, caspase-9, and caspase-3 and the proapoptotic protein Bid, but not with oxidative stress or altered levels of other Bcl-2 family proteins (Bcl-2, Bcl-xl, Mcl-1, Bax, and Bak).	salvin	24-37	caspase 3	Homo sapiens	127-136