PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19941258-1	2010	In our previous studies, we have reported that carnosic acid (CA) and carnosol (CS) originating from rosemary protects cortical neurons by inducing phase 2 enzymes, the induction of which was initiated by activation of the Keap1/Nrf2 pathway , , .	salvin	47-60	nuclear factor, erythroid derived 2, like 2	Mus musculus	229-233	
31752142-0	2019	Carnosic Acid Attenuates Cadmium Induced Nephrotoxicity by Inhibiting Oxidative Stress, Promoting Nrf2/HO-1 Signalling and Impairing TGF-beta1/Smad/Collagen IV Signalling.	salvin	0-13	nuclear factor, erythroid derived 2, like 2	Mus musculus	98-102	
30672378-6	2019	Carnosic acid (CA) has been shown to activate Nrf2 and suppress the proinflammatory transcription factor nuclear factor kappa B (NF-kappaB).	salvin	0-13	nuclear factor, erythroid derived 2, like 2	Mus musculus	46-50	
22214931-1	2012	In the previous studies, we reported that carnosic acid (CA) protects cortical neurons by activating the Keap1/Nrf2 pathway, which activation is initiated by S-alkylation of the critical cysteine thiol of the Keap1 protein by the "electrophilic"quinone-type CA.	salvin	42-55	nuclear factor, erythroid derived 2, like 2	Mus musculus	111-115	
30508646-6	2019	The pro-differentiation synergy between VDDs (1,25D3 or PRI-5202) and Nrf2 activators (DMF, tert-butylhydroquinone or carnosic acid) was associated with a cooperative upregulation of the protein levels of the vitamin D receptor (VDR) and Nrf2 as well as increased mRNA expression of their respective target genes.	salvin	118-131	nuclear factor, erythroid derived 2, like 2	Mus musculus	70-74	
30508646-6	2019	The pro-differentiation synergy between VDDs (1,25D3 or PRI-5202) and Nrf2 activators (DMF, tert-butylhydroquinone or carnosic acid) was associated with a cooperative upregulation of the protein levels of the vitamin D receptor (VDR) and Nrf2 as well as increased mRNA expression of their respective target genes.	salvin	118-131	nuclear factor, erythroid derived 2, like 2	Mus musculus	238-242	
30166101-0	2018	Carnosic acid improves diabetic nephropathy by activating Nrf2/ARE and inhibition of NF-kappaB pathway.	salvin	0-13	nuclear factor, erythroid derived 2, like 2	Mus musculus	58-62	
26807019-0	2016	Carnosic acid protects against acetaminophen-induced hepatotoxicity by potentiating Nrf2-mediated antioxidant capacity in mice.	salvin	0-13	nuclear factor, erythroid derived 2, like 2	Mus musculus	84-88	
25432068-0	2015	Nrf2-ARE activator carnosic acid decreases mitochondrial dysfunction, oxidative damage and neuronal cytoskeletal degradation following traumatic brain injury in mice.	salvin	19-32	nuclear factor, erythroid derived 2, like 2	Mus musculus	0-4	
28674855-0	2017	Carnosic acid attenuates RANKL-induced oxidative stress and osteoclastogenesis via induction of Nrf2 and suppression of NF-kappaB and MAPK signalling.	salvin	0-13	nuclear factor, erythroid derived 2, like 2	Mus musculus	96-100	
24903830-9	2014	Moreover, carnosic acid enhanced the nuclear translocation of Nrf2 and up-regulated the phase II/antioxidant enzyme activities.	salvin	10-23	nuclear factor, erythroid derived 2, like 2	Mus musculus	62-66