PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35608363-10 2022 Acetyl royleanone, 6,7-dehydroroyleanone, carnosic acid, and cryptotanshinone were found to have anticancer potential based on their modulating effects on the expression levels of Bax and Bcl-2 proteins which play important roles in the regulation of apoptosis. salvin 42-55 BCL2 associated X, apoptosis regulator Homo sapiens 180-183 30227824-8 2019 Administration of Trolox, carnosic acid and HCG increased the number of healthy cells and decreased the expression of Caspase-3 and Bax, but significantly increased the expression of Bcl-2 compared to the ischemic group. salvin 26-39 BCL2 associated X, apoptosis regulator Homo sapiens 132-135 29285102-10 2017 Furthermore, the apoptosis of H9c2 cardiomyocytes resulted from hypoxia/reoxygenation was inhibited by carnosic acid through the upregulation of Bcl-2 and the downregulation of Bax and caspase-3 levels. salvin 103-116 BCL2 associated X, apoptosis regulator Homo sapiens 177-180 28440400-7 2017 Caspase-3 signaling pathway was promoted in carnosic acid and fisetin co-treatment, which was accompanied by anti-apoptotic proteins of Bcl-2 and Bcl-xl decreasing and pro-apoptotic signals of Bax and Bad increasing. salvin 44-57 BCL2 associated X, apoptosis regulator Homo sapiens 193-196 20661831-5 2010 Early stage of curcumin/carnosic acid-induced apoptosis was associated with cleavage (activation) of caspase-8, caspase-9, and caspase-3 and the proapoptotic protein Bid, but not with oxidative stress or altered levels of other Bcl-2 family proteins (Bcl-2, Bcl-xl, Mcl-1, Bax, and Bak). salvin 24-37 BCL2 associated X, apoptosis regulator Homo sapiens 273-276