PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34048148-0 2021 Lipoxin A4 protects primary spinal cord neurons from Erastin-induced ferroptosis by activating the Akt/Nrf2/HO-1 signaling pathway. erastin 53-60 heme oxygenase 1 Homo sapiens 108-112 34048148-11 2021 In conclusion, this work demonstrated that LXA4 exerted a neuroprotective effect in Erastin-induced ferroptosis of primary spinal cord neurons by activating Akt/Nrf2/HO-1 signaling pathway. erastin 84-91 heme oxygenase 1 Homo sapiens 166-170 26403645-6 2016 Knockdown of p62, quinone oxidoreductase-1, heme oxygenase-1, and ferritin heavy chain-1 by RNA interference in HCC cells promoted ferroptosis in response to erastin and sorafenib. erastin 158-165 heme oxygenase 1 Homo sapiens 18-60 26405158-0 2015 Heme oxygenase-1 accelerates erastin-induced ferroptotic cell death. erastin 29-36 heme oxygenase 1 Homo sapiens 0-16 26405158-6 2015 Zinc protoporphyrin IX (ZnPP), a HO-1 inhibitor, prevented Erastin-triggered ferroptotic cancer cell death. erastin 59-66 heme oxygenase 1 Homo sapiens 33-37 26405158-7 2015 Furthermore, Erastin induced the protein and mRNA levels of HO-1 in HT-1080 fibrosarcoma cells. erastin 13-20 heme oxygenase 1 Homo sapiens 60-64 26405158-10 2015 In addition, hemin and CORM accelerate the HO-1 expression in the presence of Erastin and increase membranous lipid peroxidation. erastin 78-85 heme oxygenase 1 Homo sapiens 43-47