PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34722314-8 2021 Overexpressing miR-27a-3p led to SLC7A11 suppression via directly binding to its 3"-UTR, followed by the reduction of erastin-caused ferroptosis. erastin 118-125 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 Mus musculus 33-40 34749765-7 2021 PCC was highly sensitive to inhibitors of system xc- cystine/glutamate antiporter (xCT), such as erastin, sulfasalazine, and cyst(e)ine deprivation, but less sensitive to (1S,3R)-RSL3. erastin 97-104 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 Mus musculus 49-81 34749765-7 2021 PCC was highly sensitive to inhibitors of system xc- cystine/glutamate antiporter (xCT), such as erastin, sulfasalazine, and cyst(e)ine deprivation, but less sensitive to (1S,3R)-RSL3. erastin 97-104 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 Mus musculus 83-86 33019976-4 2020 We examined in vitro the effect of erastin, a specific blocker of SLC7A11, applied on two HNSCC cell lines with stable expression of HPV16 E6 and E7 oncoproteins. erastin 35-42 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 Mus musculus 66-73 34108030-17 2021 Combination of TPL with erastin, an inhibitor of SLC7A11, exerts robust synergistic effect in suppression of tumor survival in vitro and in a nude mice model. erastin 24-31 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 Mus musculus 49-56 32107878-3 2020 Here, we report that KDM3B, a histone H3 lysine 9 demethylase, can protect against ferroptosis induced by Erastin, an inhibitor of SLC7A11. erastin 106-113 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 Mus musculus 131-138 32621966-4 2020 Erastin, an inhibitor of SLC7A11, was found to hold a remarkably stronger cytotoxic effect on colorectal CSCs via in vitro and in vivo experiments. erastin 0-7 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 Mus musculus 25-32 31421954-8 2019 At 7 h after PPG administration, the efficacy of erastin, a representative xCT inhibitor, was clearly shown. erastin 49-56 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 Mus musculus 75-78 30066882-11 2018 Subsequently, activated p53 by erastin treatment suppressed SLC7A11 and induced ROS accumulation, indicating the potential feedback loop between p53 and erastin-induced ROS. erastin 31-38 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 Mus musculus 60-67 30066882-11 2018 Subsequently, activated p53 by erastin treatment suppressed SLC7A11 and induced ROS accumulation, indicating the potential feedback loop between p53 and erastin-induced ROS. erastin 153-160 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 Mus musculus 60-67 29274359-6 2018 SLC7A11 inhibition by erastin, sulfasalazine, or shRNA interference sensitizes BAY-induced cell death. erastin 22-29 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 Mus musculus 0-7