PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31323261-7	2019	Treatment with erastin upregulated Sesn2 mRNA levels and luciferase reporter gene activity, and erastin-mediated Sesn2 induction was transcriptionally regulated by NF-E2-related factor 2 (Nrf2).	erastin	15-22	nuclear factor, erythroid derived 2, like 2	Mus musculus	188-192	
31323261-8	2019	Furthermore, deletion of the antioxidant response element (ARE) in the Sesn2 promoter or Nrf2 knockout or knockdown abolished erastin-induced Sesn2 expression.	erastin	126-133	nuclear factor, erythroid derived 2, like 2	Mus musculus	89-93	
34335271-11	2021	In vitro, melatonin pretreatment reversed Erastin-induced ferroptosis, abnormalities in iron transporter protein and antioxidant enzyme expression and suppression of ERK/Nrf2 signaling in HT-22 cells, however this protective effect of melatonin was blocked by MT2-, ERK- and Nrf2-specific antagonists (p < 0.05).	erastin	42-49	nuclear factor, erythroid derived 2, like 2	Mus musculus	170-174