PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32642794-0 2020 Regulation of GSK3beta/Nrf2 signaling pathway modulated erastin-induced ferroptosis in breast cancer. erastin 56-63 glycogen synthase kinase 3 alpha Homo sapiens 14-22 32642794-6 2020 Enhanced erastin-induced ferroptosis by overexpression of GSK-3beta was blocked by activating Nrf2. erastin 9-16 glycogen synthase kinase 3 alpha Homo sapiens 58-67 32642794-7 2020 We further confirmed that overexpression of GSK-3beta strengthened erastin-induced tumor growth inhibition in breast cancer xenograft models in vivo. erastin 67-74 glycogen synthase kinase 3 alpha Homo sapiens 44-53 32642794-8 2020 In summary, our findings conclude that modulation the balance between GSK-3beta/Nrf2 is a promising therapeutic approach and probably will be important targets to enhance the effect of erastin-induced ferroptosis in breast cancer. erastin 185-192 glycogen synthase kinase 3 alpha Homo sapiens 70-79