PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24495390-5	2014	Finally, levels of HTR2A were lower in the CNS of rats treated with imipramine, but not fluoxetine, for 28 d, but not 10 d. From our current and previous data we conclude cortical HTR2A are lower in schizophrenia, MDD, people with mood disorders who died by suicide, rats treated with some antipsychotic or some antidepressant drugs.	Imipramine	68-78	5-hydroxytryptamine receptor 2A	Homo sapiens	180-185	
15181653-0	2004	Decrease of the platelet 5-HT2A receptor function by long-term imipramine treatment in endogenous depression.	Imipramine	63-73	5-hydroxytryptamine receptor 2A	Homo sapiens	25-40	
15181653-9	2004	CONCLUSIONS: The results showed a decrease in a platelet functional response mediated by 5-HT2A receptors following effective imipramine treatment, suggesting that desensitization or down-regulation of the 5-HT2A receptor function could be linked to the therapeutic effect of some antidepressants.	Imipramine	126-136	5-hydroxytryptamine receptor 2A	Homo sapiens	89-95	
15181653-9	2004	CONCLUSIONS: The results showed a decrease in a platelet functional response mediated by 5-HT2A receptors following effective imipramine treatment, suggesting that desensitization or down-regulation of the 5-HT2A receptor function could be linked to the therapeutic effect of some antidepressants.	Imipramine	126-136	5-hydroxytryptamine receptor 2A	Homo sapiens	89-104	
15214506-0	2004	Effects of myo-inositol versus fluoxetine and imipramine pretreatments on serotonin 5HT2A and muscarinic acetylcholine receptors in human neuroblastoma cells.	Imipramine	46-56	5-hydroxytryptamine receptor 2A	Homo sapiens	84-128	
15214506-3	2004	The current study aimed to investigate the possible modulatory role of mI versus fluoxetine or imipramine pretreatments on serotonin-2A receptor (5HT2A-R) and muscarinic acetylcholine receptor (mAChR) function and binding in in vitro systems.	Imipramine	95-105	5-hydroxytryptamine receptor 2A	Homo sapiens	123-144	
9754440-5	1998	When all four brain regions were taken together, a down-regulation was noted between presynaptic [3H]imipramine binding and the postsynaptic 5-HT2A receptor (r = -0.40; P = 0.0013) in the control group.	Imipramine	101-111	5-hydroxytryptamine receptor 2A	Homo sapiens	141-156