PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1829231-0	1991	Involvement of 5-HT1A activity in the discriminative stimulus effects of imipramine.	Imipramine	73-83	5-hydroxytryptamine receptor 1A	Homo sapiens	15-21	
7838924-4	1994	Imipramine decreased Bmax, reversing the effect of CMS, for beta-adrenergic and 5HT2 receptor binding, but increased Bmax for 5HT1A receptor binding.	Imipramine	0-10	5-hydroxytryptamine receptor 1A	Homo sapiens	126-140	
1762063-7	1991	Drug-appropriate responding occurred in pigeons trained at the lower dose of imipramine with the 5-HT1A compounds 8-hydroxy-2-(di-n-propylamino)tetralin hydrobromide and gepirone; partial substitution occurred in pigeons trained with the higher dose of imipramine.	Imipramine	77-87	5-hydroxytryptamine receptor 1A	Homo sapiens	97-103	
1829231-2	1991	The selective 5-HT1A agonist 8-OH-DPAT (0.03-1.0 mg/kg) resulted in dose-dependent increases in responding on the key correlated with imipramine administration.	Imipramine	134-144	5-hydroxytryptamine receptor 1A	Homo sapiens	14-20	
1829231-5	1991	The discriminative stimulus effects of imipramine were also blocked by administration of the alpha 1-adrenoceptor antagonist prazosin, suggesting a dual mediation of imipramine through both 5-HT1A and alpha 1-adrenoreceptor systems.	Imipramine	39-49	5-hydroxytryptamine receptor 1A	Homo sapiens	190-196	
1829231-5	1991	The discriminative stimulus effects of imipramine were also blocked by administration of the alpha 1-adrenoceptor antagonist prazosin, suggesting a dual mediation of imipramine through both 5-HT1A and alpha 1-adrenoreceptor systems.	Imipramine	166-176	5-hydroxytryptamine receptor 1A	Homo sapiens	190-196	
19762159-0	2010	Hormonal responses to the 5-HT1A agonist buspirone in remitted endogenous depressive patients after long-term imipramine treatment.	Imipramine	110-120	5-hydroxytryptamine receptor 1A	Homo sapiens	26-32	
19762159-4	2010	METHODS: A longitudinal design was used in 14 patients with major depressive disorder (DSM-IV) with endogenous features (Newcastle Scale) in order to assess the functional status of post-synaptic 5-HT1A receptors before and after successful antidepressant treatment with imipramine.	Imipramine	271-281	5-hydroxytryptamine receptor 1A	Homo sapiens	196-202