PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7838924-4 1994 Imipramine decreased Bmax, reversing the effect of CMS, for beta-adrenergic and 5HT2 receptor binding, but increased Bmax for 5HT1A receptor binding. Imipramine 0-10 5-hydroxytryptamine receptor 1A Homo sapiens 126-140 19762159-0 2010 Hormonal responses to the 5-HT1A agonist buspirone in remitted endogenous depressive patients after long-term imipramine treatment. Imipramine 110-120 5-hydroxytryptamine receptor 1A Homo sapiens 26-32 19762159-4 2010 METHODS: A longitudinal design was used in 14 patients with major depressive disorder (DSM-IV) with endogenous features (Newcastle Scale) in order to assess the functional status of post-synaptic 5-HT1A receptors before and after successful antidepressant treatment with imipramine. Imipramine 271-281 5-hydroxytryptamine receptor 1A Homo sapiens 196-202 1762063-7 1991 Drug-appropriate responding occurred in pigeons trained at the lower dose of imipramine with the 5-HT1A compounds 8-hydroxy-2-(di-n-propylamino)tetralin hydrobromide and gepirone; partial substitution occurred in pigeons trained with the higher dose of imipramine. Imipramine 77-87 5-hydroxytryptamine receptor 1A Homo sapiens 97-103 1829231-0 1991 Involvement of 5-HT1A activity in the discriminative stimulus effects of imipramine. Imipramine 73-83 5-hydroxytryptamine receptor 1A Homo sapiens 15-21 1829231-2 1991 The selective 5-HT1A agonist 8-OH-DPAT (0.03-1.0 mg/kg) resulted in dose-dependent increases in responding on the key correlated with imipramine administration. Imipramine 134-144 5-hydroxytryptamine receptor 1A Homo sapiens 14-20 1829231-5 1991 The discriminative stimulus effects of imipramine were also blocked by administration of the alpha 1-adrenoceptor antagonist prazosin, suggesting a dual mediation of imipramine through both 5-HT1A and alpha 1-adrenoreceptor systems. Imipramine 39-49 5-hydroxytryptamine receptor 1A Homo sapiens 190-196 1829231-5 1991 The discriminative stimulus effects of imipramine were also blocked by administration of the alpha 1-adrenoceptor antagonist prazosin, suggesting a dual mediation of imipramine through both 5-HT1A and alpha 1-adrenoreceptor systems. Imipramine 166-176 5-hydroxytryptamine receptor 1A Homo sapiens 190-196