PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21067755-1 2011 Carbamazepine and imipramine are drugs that have significant binding to human serum albumin (HSA), the most abundant serum protein in blood and a common transport protein for many drugs in the body. Imipramine 18-28 albumin Homo sapiens 78-91 21067755-1 2011 Carbamazepine and imipramine are drugs that have significant binding to human serum albumin (HSA), the most abundant serum protein in blood and a common transport protein for many drugs in the body. Imipramine 18-28 albumin Homo sapiens 93-96 21067755-3 2011 In this report, an approach based on peak profiling was used with high-performance affinity chromatography to measure the dissociation rate constants for carbamazepine and imipramine with HSA. Imipramine 172-182 albumin Homo sapiens 188-191 21067755-6 2011 Dissociation rate constants of 1.7 (+-0.2) s(-1) and 0.67 (+-0.04) s(-1) at pH 7.4 and 37 C were estimated by this approach for HSA in its interactions with carbamazepine and imipramine, respectively. Imipramine 175-185 albumin Homo sapiens 128-131 15132707-1 2004 Interactions of two amphiphilic antidepressant drugs, imipramine and desipramine hydrochlorides, with the blood protein human serum albumin (HSA) were investigated to gain an understanding of the effects of drug molecular structure on the complex formation of drug-protein molecules. Imipramine 54-64 albumin Homo sapiens 126-139 19328747-0 2009 Studies of imipramine binding to human serum albumin by high-performance affinity chromatography. Imipramine 11-21 albumin Homo sapiens 39-52 19328747-1 2009 Binding by the drug imipramine to the protein human serum albumin (HSA) was studied by using high-performance affinity chromatography. Imipramine 20-30 albumin Homo sapiens 52-65