PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28462695-5	2017	RESULTS: Here we show that the enhancement of the phosphorylation of CREB Ser133 and expression of CREB and glutamate receptor 1 (GluR1) are necessary for both ketamine"s and imipramine"s antidepressant actions, but the enhancements at early stage may account for the faster onset of ketamine"s antidepressant action than imipramine.	Imipramine	175-185	glutamate ionotropic receptor AMPA type subunit 1	Homo sapiens	108-128	
28462695-5	2017	RESULTS: Here we show that the enhancement of the phosphorylation of CREB Ser133 and expression of CREB and glutamate receptor 1 (GluR1) are necessary for both ketamine"s and imipramine"s antidepressant actions, but the enhancements at early stage may account for the faster onset of ketamine"s antidepressant action than imipramine.	Imipramine	175-185	glutamate ionotropic receptor AMPA type subunit 1	Homo sapiens	130-135	
28462695-5	2017	RESULTS: Here we show that the enhancement of the phosphorylation of CREB Ser133 and expression of CREB and glutamate receptor 1 (GluR1) are necessary for both ketamine"s and imipramine"s antidepressant actions, but the enhancements at early stage may account for the faster onset of ketamine"s antidepressant action than imipramine.	Imipramine	322-332	glutamate ionotropic receptor AMPA type subunit 1	Homo sapiens	108-128	
28462695-5	2017	RESULTS: Here we show that the enhancement of the phosphorylation of CREB Ser133 and expression of CREB and glutamate receptor 1 (GluR1) are necessary for both ketamine"s and imipramine"s antidepressant actions, but the enhancements at early stage may account for the faster onset of ketamine"s antidepressant action than imipramine.	Imipramine	322-332	glutamate ionotropic receptor AMPA type subunit 1	Homo sapiens	130-135	
16936714-2	2007	Chronic treatment with the antimanic agents, lithium and valproate, resulted in reduced synaptic expression of the AMPA(-amino-3-hydroxy-5-methylisoxazole-4-propionic acid) receptor subunit GluR1 in the hippocampus, while treatment with an antidepressant (imipramine) enhanced the synaptic expression of GluR1.	Imipramine	256-266	glutamate ionotropic receptor AMPA type subunit 1	Homo sapiens	190-195	
16936714-9	2007	In addition, lamotrigine and riluzole, as well as the traditional antidepressant imipramine, also increased GluR1 phosphorylation at GluR1 (S845) in the hippocampus after chronic in vivo treatment.	Imipramine	81-91	glutamate ionotropic receptor AMPA type subunit 1	Homo sapiens	108-113	
16936714-9	2007	In addition, lamotrigine and riluzole, as well as the traditional antidepressant imipramine, also increased GluR1 phosphorylation at GluR1 (S845) in the hippocampus after chronic in vivo treatment.	Imipramine	81-91	glutamate ionotropic receptor AMPA type subunit 1	Homo sapiens	133-138