PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24761678-10 2013 The protein expression of BDNF in brain was more in imipramine, high dose,exercise and joint groups than that of control group, sports group was higher than that of low dose and high dose group, joint group was obviously higher than other groups. Imipramine 52-62 brain derived neurotrophic factor Mus musculus 26-30 26481532-4 2015 OBJECTIVE AND METHODS: In the present study we investigated whether acute or chronic treatment with imipramine, escitalopram, reboxetine and bupropion would cause changes in CREB, BDNF, TrkB and GPR39-Zn(2+) receptor proteins (measured by Western Blot) in the frontal cortex of mice fed with a low-zinc diet. Imipramine 100-110 brain derived neurotrophic factor Mus musculus 180-184 26481532-5 2015 RESULTS: The administration of acute antidepressants induced diverse effects in the proteins that were examined (namely, GPR39 down-regulation and a reduction in CREB protein after administration of all ADs; a decrease in BDNF after administration of imipramine and escitalopram; an increase in BDNF after administration of reboxetine; no change in BDNF following administration of bupropion; and a decrease in TrkB following the administration of all ADs except bupropion). Imipramine 251-261 brain derived neurotrophic factor Mus musculus 222-226 26921875-9 2016 Intraperitoneal injection of imipramine or histone deacetylase inhibitors (HDACi) to the LH mice for 14 consecutive days ameliorated depression-like behaviors and reversed the decrease in BDNF. Imipramine 29-39 brain derived neurotrophic factor Mus musculus 188-192 20089918-7 2010 Furthermore, coadministration of the alpha(2)-adrenoceptor antagonist yohimbine with the antidepressant imipramine significantly accelerates effects on hippocampal progenitor proliferation, the morphological maturation of newborn neurons, and the increase in expression of brain derived neurotrophic factor and vascular endothelial growth factor implicated in the neurogenic and behavioral effects of antidepressants. Imipramine 104-114 brain derived neurotrophic factor Mus musculus 273-306 22310305-9 2013 Finally, chronic administration of imipramine significantly increased mBDNF levels, but not pro-BDNF and protease levels, indicating that the therapeutic mechanism of imipramine differs from that of ECS. Imipramine 35-45 brain derived neurotrophic factor Mus musculus 70-75 21867718-8 2012 As previously reported, the effects of imipramine in the forced swim test were blunted in heterozygous BDNF knockout (bdnf(+/-)) mice. Imipramine 39-49 brain derived neurotrophic factor Mus musculus 103-107 21867718-8 2012 As previously reported, the effects of imipramine in the forced swim test were blunted in heterozygous BDNF knockout (bdnf(+/-)) mice. Imipramine 39-49 brain derived neurotrophic factor Mus musculus 118-122 21666748-6 2011 However, the tricyclic AD imipramine readily induced the phosphorylation of TrkB receptors in conditional bdnf-/- knock-out mice (132.4+-8.5% of control; P = 0.01), indicating that BDNF is not required for the TrkB activation. Imipramine 26-36 brain derived neurotrophic factor Mus musculus 106-110 21666748-6 2011 However, the tricyclic AD imipramine readily induced the phosphorylation of TrkB receptors in conditional bdnf-/- knock-out mice (132.4+-8.5% of control; P = 0.01), indicating that BDNF is not required for the TrkB activation. Imipramine 26-36 brain derived neurotrophic factor Mus musculus 181-185 21856315-8 2012 Furthermore, chronic co-administration of SRA880 and imipramine synergistically increased BDNF mRNA expression in the cerebral cortex. Imipramine 53-63 brain derived neurotrophic factor Mus musculus 90-94 16519925-6 2006 Repeated treatment with antidepressant drugs, imipramine (Imi) and fluoxetine (Flu), significantly reduced the plasma corticosterone concentration and enhanced the BDNF and CREB levels. Imipramine 46-56 brain derived neurotrophic factor Mus musculus 164-168 16519925-6 2006 Repeated treatment with antidepressant drugs, imipramine (Imi) and fluoxetine (Flu), significantly reduced the plasma corticosterone concentration and enhanced the BDNF and CREB levels. Imipramine 58-61 brain derived neurotrophic factor Mus musculus 164-168 15157811-2 2004 Furthermore, we show that both eugenol and imipramine induce brain-derived neurotrophic factor (BDNF) in the hippocampus with and without induction of metallothionein-III (MT-III), respectively. Imipramine 43-53 brain derived neurotrophic factor Mus musculus 61-94 15157811-2 2004 Furthermore, we show that both eugenol and imipramine induce brain-derived neurotrophic factor (BDNF) in the hippocampus with and without induction of metallothionein-III (MT-III), respectively. Imipramine 43-53 brain derived neurotrophic factor Mus musculus 96-100 19463708-7 2009 Furthermore, imipramine induced a twofold increase of bdnf expression in the dentate gyrus in both genotypes, while bdnf(+/-) mice displayed roughly half-reduced level for the same treatment. Imipramine 13-23 brain derived neurotrophic factor Mus musculus 54-58 34421682-7 2021 GUO and IMI reversed the OBX-induced hyperlocomotion and recognition memory impairment, hippocampal BDNF increase, and redox imbalance (ROS, NO, and GSH levels). Imipramine 8-11 brain derived neurotrophic factor Mus musculus 100-104 29358904-6 2017 Other antidepressants (e.g., sertraline and imipramine) also increased the expression of BDNF mRNA with relative potencies similar to those for inhibition of Kir4.1 channels. Imipramine 44-54 brain derived neurotrophic factor Mus musculus 89-93