PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30500605-8	2019	To confirm ezetimibe regulatory role on Apo A-II expression, siRNA against HNF4, PPARalpha, and SREBP1 were transfected into HepG2 cells.	Ezetimibe	11-20	apolipoprotein A2	Homo sapiens	40-48	
30500605-9	2019	RESULTS: The results show that ezetimibe increased the expression of Apo A-II but failed to reduce vascular lipid accumulation and macrophage recruitment induced by the HCD diet when Apo A-II was knocked down.	Ezetimibe	31-40	apolipoprotein A2	Homo sapiens	69-77	
30500605-10	2019	Finally, we found that ezetimibe increased the expression of Apo A-II through HNF4 and PPARalpha transcriptional factors.	Ezetimibe	23-32	apolipoprotein A2	Homo sapiens	61-69	
30500605-11	2019	CONCLUSIONS: Our data indicates that ezetimibe may not only prevents atherosclerosis by inhibiting cholesterol absorption in the intestine, but also by increasing the expression of Apo A-II in hepatocytes, thereby enhancing reverse cholesterol transport and removing excess cholesterol from the periphery.	Ezetimibe	37-46	apolipoprotein A2	Homo sapiens	181-189