PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22523394-7	2012	Expression of inducible degrader of LDLR (IDOL), an LXR-regulated gene that degrades LDLRs, was reduced 50% by ezetimibe.	Ezetimibe	111-120	nuclear receptor subfamily 1, group H, member 3	Mus musculus	52-55	
22523394-8	2012	Coadministration of ezetimibe with the LXR agonist T0901317 abolished the reduction in IDOL and prevented the increase in LDLR protein.	Ezetimibe	20-29	nuclear receptor subfamily 1, group H, member 3	Mus musculus	39-42	
30045953-9	2018	Moreover, heightened sensitivity to HCD cannot be reversed by ezetimibe, a Niemann-Pick C1-like 1 inhibitor that inhibits intestinal cholesterol absorption, suggesting that the increased cholesterol absorption in LXR-activated intestine is mediated by a mechanism that has yet to be defined.	Ezetimibe	62-71	nuclear receptor subfamily 1, group H, member 3	Mus musculus	213-216	
24773344-11	2014	Therefore, in obese subjects, ezetimibe reduces hepatic LXR activity by reducing hepatic oxysterols to lower hepatic oleate content.	Ezetimibe	30-39	nuclear receptor subfamily 1, group H, member 3	Mus musculus	56-59	
18318438-4	2008	Interestingly, the lithogenic effect of LXR was completely abolished in the low-density lipoprotein receptor (Ldlr) null background or when the mice were treated with Ezetimibe, a cholesterol-lowering drug that blocks intestinal dietary cholesterol absorption.	Ezetimibe	167-176	nuclear receptor subfamily 1, group H, member 3	Mus musculus	40-43	
24163219-1	2014	We investigated whether: (1) liver X receptor (LXR)-driven induction of high-density lipoprotein cholesterol (HDL-C) and other LXR-mediated effects on cholesterol metabolism depend on intestinal cholesterol absorption; and (2) combined treatment with the LXR agonist GW3965 and the cholesterol absorption inhibitor ezetimibe results in synergistic effects on cholesterol metabolism that could be beneficial for treatment of atherosclerosis.	Ezetimibe	315-324	nuclear receptor subfamily 1, group H, member 3	Mus musculus	47-50