PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22327624-2 2012 The KIF5B-RET fusion leads to aberrant activation of RET kinase and is considered to be a new driver mutation of LADC because it segregates from mutations or fusions in EGFR, KRAS, HER2 and ALK, and a RET tyrosine kinase inhibitor, vandetanib, suppresses the fusion-induced anchorage-independent growth activity of NIH3T3 cells. vandetanib 232-242 anaplastic lymphoma kinase Mus musculus 190-193