PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28413487-4 2017 Vandetanib suppressed the expression of the mesenchymal markers ADAM10 and ADAM17 in ARPE19/EBV cells, and also upregulated epithelial cell markers of the RPE cells, E-cadherin and N-cadherin. vandetanib 0-10 ADAM metallopeptidase domain 10 Homo sapiens 64-70 28413487-6 2017 Furthermore, co-treatment with vandetanib and an ADAM10 inhibitor (GI254023X) or ADAM17 inhibitor (Marimastat) synergistically prevented migration and the expression of vimentin, Snail and alpha-smooth muscle actin by regulating extracellular signal-regulated kinase and p38 mitogen-activated protein kinase. vandetanib 31-41 ADAM metallopeptidase domain 10 Homo sapiens 49-55