PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24138843-10 2013 The combination of ZD6474 with UV-B vs. either agent alone also more potently down-regulated the anti-apoptotic bcl-2 protein, up-regulated pro-apoptotic signaling events involving expression of bax, activation of caspase-3 and caspase-7 proteins, and induced poly (ADP-ribose) polymerase resulting in apoptosis. vandetanib 19-25 caspase 7 Homo sapiens 228-237 20665703-7 2011 The combination of ZD6474 with paclitaxel versus either agent alone also more potently down-regulated the antiapoptotic bcl-2 protein, up-regulated pro-apoptotic signaling events involving expression of bax, activation of caspase-3 and caspase-7 proteins, and induced poly(ADP-ribose) polymerase resulting in apoptosis. vandetanib 19-25 caspase 7 Homo sapiens 236-245