PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29436676-8	2018	Vandetanib significantly inhibited SH-SY5Y-R cell proliferation, colony formation, and invasion, while downregulating p-RET and CXCR4 expression.	vandetanib	0-10	C-X-C motif chemokine receptor 4	Homo sapiens	128-133	
24399074-0	2014	Vandetanib-induced inhibition of neuroblastoma cell migration and invasion is associated with downregulation of the SDF-1/CXCR4 axis and matrix metalloproteinase 14.	vandetanib	0-10	C-X-C motif chemokine receptor 4	Homo sapiens	122-127	
25676691-4	2015	VEGFR signaling inhibitors (Cediranib and Vandetanib) elevated the expression of CXCR4 in VEGFR-expressing GBM cell lines and tumors, and enhanced the in vitro migration of these lines toward CXCL12.	vandetanib	42-52	C-X-C motif chemokine receptor 4	Homo sapiens	81-86	
24399074-8	2014	In addition, our data showed that the levels of C-X-C chemokine receptor type 4 (CXCR4) and matrix metalloproteinase 14 (MMP14) mRNA expression in NB cell lines treated with vandetanib were significantly lower than those in the cells that were treated with vehicle (p<0.01) and similar results were obtained for protein levels as determined by western blotting and immunofluorescence analysis.	vandetanib	174-184	C-X-C motif chemokine receptor 4	Homo sapiens	48-79	
24399074-8	2014	In addition, our data showed that the levels of C-X-C chemokine receptor type 4 (CXCR4) and matrix metalloproteinase 14 (MMP14) mRNA expression in NB cell lines treated with vandetanib were significantly lower than those in the cells that were treated with vehicle (p<0.01) and similar results were obtained for protein levels as determined by western blotting and immunofluorescence analysis.	vandetanib	174-184	C-X-C motif chemokine receptor 4	Homo sapiens	81-86	
24399074-10	2014	The potential mechanisms for the inhibition of NB migration and invasion by vandetanib may partly be attributed to the ability of vandetanib to suppress the expression of CXCR4 and MMP14 in human NB cells.	vandetanib	76-86	C-X-C motif chemokine receptor 4	Homo sapiens	171-176	
24399074-10	2014	The potential mechanisms for the inhibition of NB migration and invasion by vandetanib may partly be attributed to the ability of vandetanib to suppress the expression of CXCR4 and MMP14 in human NB cells.	vandetanib	130-140	C-X-C motif chemokine receptor 4	Homo sapiens	171-176