PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29630634-4	2018	Purkinje fiber assays and ion channel studies showed that vandetanib at concentrations of 1 and 3 muM inhibited the hERG currents and prolonged the action potential duration.	vandetanib	58-68	ETS transcription factor ERG	Homo sapiens	116-120	
34659631-5	2021	Therefore, in this study, we aim to confirm whether ginsenoside Rg3 targeting hERG K(+) channel could be used to reverse the vandetanib-induced QT interval prolongation.	vandetanib	125-135	ETS transcription factor ERG	Homo sapiens	78-82	
34659631-11	2021	In stable transfected human hERG gene HEK293 cells, vandetanib caused concentrate-dependent inhibition in the step and tail currents of hERG.	vandetanib	52-62	ETS transcription factor ERG	Homo sapiens	28-32	
34659631-11	2021	In stable transfected human hERG gene HEK293 cells, vandetanib caused concentrate-dependent inhibition in the step and tail currents of hERG.	vandetanib	52-62	ETS transcription factor ERG	Homo sapiens	136-140	
34659631-13	2021	Furthermore, ginsenoside Rg3 alleviated vandetanib-induced hERG current inhibition and accelerated the process of the channel activation.	vandetanib	40-50	ETS transcription factor ERG	Homo sapiens	59-63	
29630634-5	2018	Alanine scanning and in silico hERG docking studies demonstrated that Y652 and F656 in the hERG S6 domain play critical roles in vandetanib binding.	vandetanib	129-139	ETS transcription factor ERG	Homo sapiens	31-35	
29630634-5	2018	Alanine scanning and in silico hERG docking studies demonstrated that Y652 and F656 in the hERG S6 domain play critical roles in vandetanib binding.	vandetanib	129-139	ETS transcription factor ERG	Homo sapiens	91-95