PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30774369-0 2019 Avasimibe inhibits tumor growth by targeting FoxM1-AKR1C1 in osteosarcoma. avasimibe 0-9 forkhead box M1 Homo sapiens 45-50 34127944-0 2021 Avasimibe Dampens Cholangiocarcinoma Progression by Inhibiting FoxM1-AKR1C1 Signaling. avasimibe 0-9 forkhead box M1 Homo sapiens 63-68 34127944-2 2021 In the study, we proved that avasimibe retard cell proliferation and tumor growth of CCAs and identified FoxM1/AKR1C1 axis as the potential novel targets of avasimibe. avasimibe 157-166 forkhead box M1 Homo sapiens 105-110 34127944-7 2021 Moreover, over-expressing exogenous FoxM1 reverses the growth retardation of CCA cells induced by avasimibe administration, while silencing AKR1C1 in FoxM1-overexpressing again retard cell growth. avasimibe 98-107 forkhead box M1 Homo sapiens 36-41 34127944-9 2021 Our study demonstrates a novel positive regulatory between FoxM1 and AKR1C1 contributing cell growth and tumor progression of CCA and avasimibe may be an alternative therapeutic option for CCA by targeting this FoxM1/AKR1C1 signaling pathway. avasimibe 134-143 forkhead box M1 Homo sapiens 59-64 34127944-9 2021 Our study demonstrates a novel positive regulatory between FoxM1 and AKR1C1 contributing cell growth and tumor progression of CCA and avasimibe may be an alternative therapeutic option for CCA by targeting this FoxM1/AKR1C1 signaling pathway. avasimibe 134-143 forkhead box M1 Homo sapiens 211-216 30774369-6 2019 Avasimibe was found to inhibit cell proliferation and tumor growth by reducing the expression of AKR1C1 and FoxM1 in vivo and in vitro. avasimibe 0-9 forkhead box M1 Homo sapiens 108-113