PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10421659-0 1999 Acyl-coenzyme A:cholesterol acyltransferase inhibitor, avasimibe, stimulates bile acid synthesis and cholesterol 7alpha-hydroxylase in cultured rat hepatocytes and in vivo in the rat. avasimibe 55-64 cytochrome P450 family 7 subfamily A member 1 Rattus norvegicus 101-131 10421659-4 1999 Avasimibe (3 micromol/L) increased bile acid synthesis (2.9-fold) after preincubation with betaVLDL and cholesterol 7alpha-hydroxylase activity (1.7- and 2.6-fold, with or without betaVLDL), the latter paralleled by a similar induction of its messenger RNA (mRNA). avasimibe 0-9 cytochrome P450 family 7 subfamily A member 1 Rattus norvegicus 104-134