PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31423222-4	2019	Western blotting, immunofluorescence microscopy and flow cytometry allowed the present study to determine that the ACAT-1 inhibitor avasimibe significantly reduced the expression of ACAT-1 in LLC compared with LLC cells that are not treated with avasimibe (P<0.05).	avasimibe	132-141	acetyl-Coenzyme A acetyltransferase 1	Mus musculus	182-188	
28719608-7	2017	Blocking cholesterol esterification with avasimibe, a potent inhibitor of acyl-CoA cholesterol acyltransferase 1 (ACAT-1), significantly suppressed CML cell proliferation in Ba/F3 cells with the BCR-ABLT315I mutation and in K562 cells rendered imatinib resistant without mutations in the BCR-ABL kinase domain (K562R cells).	avasimibe	41-50	acetyl-Coenzyme A acetyltransferase 1	Mus musculus	74-112	
28719608-7	2017	Blocking cholesterol esterification with avasimibe, a potent inhibitor of acyl-CoA cholesterol acyltransferase 1 (ACAT-1), significantly suppressed CML cell proliferation in Ba/F3 cells with the BCR-ABLT315I mutation and in K562 cells rendered imatinib resistant without mutations in the BCR-ABL kinase domain (K562R cells).	avasimibe	41-50	acetyl-Coenzyme A acetyltransferase 1	Mus musculus	114-120	
34371065-4	2021	METHODS: We administrated avasimibe, an ACAT inhibitor, or vehicle to high-fat diet-induced obese (DIO) mice via intraperitoneal injection and evaluated adiposity, food intake, energy expenditure, and glucose homeostasis.	avasimibe	26-35	acetyl-Coenzyme A acetyltransferase 1	Mus musculus	40-44	
31423222-4	2019	Western blotting, immunofluorescence microscopy and flow cytometry allowed the present study to determine that the ACAT-1 inhibitor avasimibe significantly reduced the expression of ACAT-1 in LLC compared with LLC cells that are not treated with avasimibe (P<0.05).	avasimibe	132-141	acetyl-Coenzyme A acetyltransferase 1	Mus musculus	115-121	
11282910-1	2001	BACKGROUND: The present study investigated whether the ACAT inhibitor avasimibe can reduce atherogenesis independently of its cholesterol-lowering effect in ApoE*3-Leiden mice.	avasimibe	70-79	acetyl-Coenzyme A acetyltransferase 1	Mus musculus	55-59