PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20844195-7 2010 Lfng modification of O-fucose in the Notch1 ligand-binding domain contributed to but was not solely responsible for the developmental effects of Lfng overexpression. o-fucose 21-29 LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase Homo sapiens 0-4 20844195-7 2010 Lfng modification of O-fucose in the Notch1 ligand-binding domain contributed to but was not solely responsible for the developmental effects of Lfng overexpression. o-fucose 21-29 LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase Homo sapiens 145-149 32820046-8 2020 Mutagenesis studies showed that LFNG modification of O-fucose on EGF8 and 12 of NOTCH2 was responsible for enhancement of DLL1-NOTCH2 activation, similar to previous reports for NOTCH1. o-fucose 53-61 LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase Homo sapiens 32-36 19028689-5 2009 A mutagenesis strategy for Lfng was guided by a multiple sequence alignment of Fringe proteins and solutions from docking an epidermal growth factor-like O-fucose acceptor substrate onto a homology model of Lfng. o-fucose 154-162 LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase Homo sapiens 27-31 32820046-10 2020 Interestingly, elimination of the O-fucose site on EGF12 allowed LFNG to inhibit JAG1-NOTCH2 activation, and O-fucosylation on EGF9 was important for trafficking of both NOTCH1 and NOTCH2. o-fucose 34-42 LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase Homo sapiens 65-69