PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34321365-7	2022	Additionally, shikonin decreased the migration of SNU-C5RR cells via the upregulation of E-cadherin and downregulation of N-cadherin.	shikonin	14-22	cadherin 1	Homo sapiens	89-99	
31071331-11	2019	Histological analysis confirmed that shikonin elevated levels of E-cadherin, phosphorylated beta-catenin, and GSK-3beta, and decreased levels of vimentin and beta-catenin in pulmonary metastatic foci.	shikonin	37-45	cadherin 1	Homo sapiens	65-75	
32103900-12	2020	In addition, shikonin decreased Vimentin, increased E-cadherin protein expressions and E-cadherin promoter activity, the latter was reversed in cells transfected with exogenous Snail overexpression vectors.	shikonin	13-21	cadherin 1	Homo sapiens	52-62	
32103900-12	2020	In addition, shikonin decreased Vimentin, increased E-cadherin protein expressions and E-cadherin promoter activity, the latter was reversed in cells transfected with exogenous Snail overexpression vectors.	shikonin	13-21	cadherin 1	Homo sapiens	87-97	
32103900-13	2020	Moreover, silencing of E-cadherin significantly abolished shikonin-inhibited cervical cancer cell growth.	shikonin	58-66	cadherin 1	Homo sapiens	23-33	
32103900-15	2020	Conclusion: Our results show that shikonin inhibits EMT through inhibition of Snail and stimulation of miR-183-5p expressions, which resulted in induction of E-cadherin expression.	shikonin	34-42	cadherin 1	Homo sapiens	158-168