PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30098030-0	2018	Overexpression of Ecm22 improves ergosterol biosynthesis in Saccharomyces cerevisiae.	Ergosterol	33-43	Ecm22p	Saccharomyces cerevisiae S288C	18-23	
30098030-2	2018	To clarify the influence of transcriptional regulation on the ergosterol content, transcription factor Ecm22 was overexpressed in S. cerevisiae.	Ergosterol	62-72	Ecm22p	Saccharomyces cerevisiae S288C	103-108	
30098030-6	2018	Among truncated ECM22 fragments, only the 1440-bp DNA fragment exerted almost the same impact on ergosterol content as that of the full-length gene.	Ergosterol	97-107	Ecm22p	Saccharomyces cerevisiae S288C	16-21	
21199190-1	2011	Zn[2]-Cys[6] binuclear transcription factors Upc2p and Ecm22p regulate the expression of genes involved in ergosterol biosynthesis and exogenous sterol uptake in Saccharomyces cerevisiae.	Ergosterol	107-117	Ecm22p	Saccharomyces cerevisiae S288C	55-61	
24867980-2	2014	Upc2 and Ecm22 in Saccharomyces cerevisiae and Upc2 in Candida albicans are the transcriptional regulators of ERG11, the gene encoding the target of azoles in the ergosterol biosynthesis pathway.	Ergosterol	163-173	Ecm22p	Saccharomyces cerevisiae S288C	9-14	
16055745-2	2005	Two transcription factors, Upc2p and Ecm22p, bind to the promoters of most ergosterol biosynthetic (ERG) genes, including ERG2 and ERG3, and activate these genes upon sterol depletion.	Ergosterol	75-85	Ecm22p	Saccharomyces cerevisiae S288C	37-43	
16783004-1	2006	Upc2p and Ecm22p are a pair of transcription factors responsible for the basal and induced expression of genes encoding enzymes of ergosterol biosynthesis in yeast (ERG genes).	Ergosterol	131-141	Ecm22p	Saccharomyces cerevisiae S288C	10-16	
18675371-2	2008	Paralogous zinc cluster transcription factors Upc2p and Ecm22p are major regulators of ergosterol biosynthesis in Saccharomyces cerevisiae.	Ergosterol	87-97	Ecm22p	Saccharomyces cerevisiae S288C	56-62	
18675371-6	2008	Perinuclear localization of Upc2p-GFP and Ecm22p-GFP was increased when ergosterol biosynthesis was blocked by azole drug treatment.	Ergosterol	72-82	Ecm22p	Saccharomyces cerevisiae S288C	42-48	
15855491-4	2005	In Saccharomyces cerevisiae, two highly related transcriptional activators, Upc2p and Ecm22p, positively regulate the expression of genes involved in ergosterol synthesis (ERG genes).	Ergosterol	150-160	Ecm22p	Saccharomyces cerevisiae S288C	86-92	
15590814-2	2004	A search of the C. albicans genome identified a single homolog of the S. cerevisiae transcription factor genes UPC2 (ScUPC2) and ECM22 (ScECM22) that have been associated with regulation of ergosterol biosynthesis.	Ergosterol	190-200	Ecm22p	Saccharomyces cerevisiae S288C	129-134