PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22252807-1 2012 The inactivation of ERG3, a gene encoding sterol Delta5,6-desaturase (essential for ergosterol biosynthesis), is a known mechanism of in vitro resistance to azole antifungal drugs in the human pathogen Candida albicans. Ergosterol 84-94 sterol-C5-desaturase Homo sapiens 20-24 8978840-3 1996 The delta 5-double bond appears to be required for the regulatory role of ergosterol; therefore, development of inhibitors of the enzyme that introduce this double bond, delta 7-sterol 5-desaturase (5-desaturase), may lead to effective antifungal agents. Ergosterol 74-84 sterol-C5-desaturase Homo sapiens 170-197 35025137-9 2022 Anu taila downregulated sterol-C5-desaturase-coding ERG3 gene, crucial for ergosterol biosynthesis and resultant structural integrity, in Mucor spp. Ergosterol 75-85 sterol-C5-desaturase Homo sapiens 24-44 35025137-9 2022 Anu taila downregulated sterol-C5-desaturase-coding ERG3 gene, crucial for ergosterol biosynthesis and resultant structural integrity, in Mucor spp. Ergosterol 75-85 sterol-C5-desaturase Homo sapiens 52-56