PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16687393-4 2006 This effect was reversed by the proteasome inhibitor epoxomicin, suggesting a Sir2alpha-mediated ubiquitin/proteasome-dependent mechanism for degradation of H2A.z. epoxomicin 53-63 sirtuin 1 Homo sapiens 78-87