PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35222798-7 2022 Conversely, administration of epoxomicin (a selective proteasome inhibitor) markedly mitigated Ang II-induced cardiac edema, remodeling, and dysfunction; upregulated MKP5 and VE-cadherin expression; inactivated p38 MAPK; and reduced lymphatic vessel hyperpermeability in WT mice, indicating that inhibition of proteasome activity is required to maintain lymphatic endothelial cell (LEC) integrity. epoxomicin 30-40 cadherin 5 Mus musculus 175-186