PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31835640-1 2019 Vortioxetine is a novel, multimodal antidepressant with unique targets, including the inhibition of the serotonin transporter (SET), of serotonin 5-HT3 (5-HT3R), and of 5-HT7 (5-HT7R) receptors and partial agonism to serotonin 5-HT1A (5-HT1AR) receptors in humans. Vortioxetine 0-12 5-hydroxytryptamine receptor 7 Homo sapiens 169-174 31835640-1 2019 Vortioxetine is a novel, multimodal antidepressant with unique targets, including the inhibition of the serotonin transporter (SET), of serotonin 5-HT3 (5-HT3R), and of 5-HT7 (5-HT7R) receptors and partial agonism to serotonin 5-HT1A (5-HT1AR) receptors in humans. Vortioxetine 0-12 5-hydroxytryptamine receptor 7 Homo sapiens 176-182 31835640-2 2019 Vortioxetine has a lower affinity to 5-HT1AR and 5-HT7R in rats compared with humans, but several behavior studies have demonstrated its powerful antidepressant-like actions. Vortioxetine 0-12 5-hydroxytryptamine receptor 7 Homo sapiens 49-55