PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29514282-3 2018 Taking into consideration that vortioxetine increases spine number and dendritic branching in hippocampus CA1 faster than fluoxetine, we hypothesize that new spines induced by vortioxetine can rapidly form functional synapses by mitochondrial support, accompanied by increased brain-derived neurotrophic factor signaling. Vortioxetine 31-43 carbonic anhydrase 1 Rattus norvegicus 106-109 29274875-3 2018 Furthermore, we studied the effects of vortioxetine on activity of CA1 Stratum Radiatum interneurons in rat hippocampus slices using current- and voltage-clamping methods. Vortioxetine 39-51 carbonic anhydrase 1 Rattus norvegicus 67-70 29274875-8 2018 Finally, in 5-HT3 receptor-expressing GABAergic interneurons from the CA1 stratum radiatum, vortioxetine and ondansetron blocked depolarizations induced by superfusion of either 5-HT or the 5-HT3 receptor agonist mCPBG. Vortioxetine 92-104 carbonic anhydrase 1 Rattus norvegicus 70-73 29514282-3 2018 Taking into consideration that vortioxetine increases spine number and dendritic branching in hippocampus CA1 faster than fluoxetine, we hypothesize that new spines induced by vortioxetine can rapidly form functional synapses by mitochondrial support, accompanied by increased brain-derived neurotrophic factor signaling. Vortioxetine 176-188 carbonic anhydrase 1 Rattus norvegicus 106-109 25122043-4 2014 Vortioxetine was found to prevent the 5-HT-induced increase in inhibitory post-synaptic potentials recorded from CA1 pyramidal cells, most likely by 5-HT3 receptor antagonism. Vortioxetine 0-12 carbonic anhydrase 1 Rattus norvegicus 113-116 25122043-5 2014 Vortioxetine also enhanced LTP in the CA1 region of the hippocampus. Vortioxetine 0-12 carbonic anhydrase 1 Rattus norvegicus 38-41