PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33649853-0 2021 Lycorine inhibits cell proliferation, migration and invasion, and primarily exerts in vitro cytostatic effects in human colorectal cancer via activating the ROS/p38 and AKT signaling pathways. lycorine 0-8 mitogen-activated protein kinase 14 Homo sapiens 161-164 33649853-12 2021 The intracellular reactive oxygen species (ROS) measurement results also indicated that compared with the control group, lycorine significantly induced ROS accumulation, and increased phosphorylated-p38 expression levels and AKT phosphorylation. lycorine 121-129 mitogen-activated protein kinase 14 Homo sapiens 199-202 33649853-13 2021 Collectively, the present study suggested that lycorine might induce cell cycle arrest and exert cytostatic effects potentially via activating ROS/p38 and AKT signaling pathways in CRC cells. lycorine 47-55 mitogen-activated protein kinase 14 Homo sapiens 147-150 31464976-0 2020 Lycorine Induces Apoptosis and G1 Phase Arrest Through ROS/p38 MAPK Signaling Pathway in Human Osteosarcoma cells in vitro and in vivo. lycorine 0-8 mitogen-activated protein kinase 14 Homo sapiens 59-62 31464976-8 2020 Inhibition of ROS generation by NAC or p38 MAPK signaling by SB203580 attenuated the p53-mediated cell cycle arrest and apoptosis induced by LY. lycorine 141-143 mitogen-activated protein kinase 14 Homo sapiens 39-42