PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23176676-15 2012 Lycorine treatment also significantly upregulated the expression of p53 and its target gene product, p21. lycorine 0-8 cyclin dependent kinase inhibitor 1A Homo sapiens 101-104 33649853-11 2021 Furthermore, lycorine significantly downregulated the protein expression levels of cyclin D1 and cyclin E1, but significantly increased p21 and Smad4 protein expression levels in HCT116 and LoVo cells compared with the control group. lycorine 13-21 cyclin dependent kinase inhibitor 1A Homo sapiens 136-139