PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32885412-5 2021 Rimonabant alone stimulates protein synthesis in a time- and dose-dependent manner through mTOR- and intracellular calcium-dependent mechanisms. Rimonabant 0-10 mechanistic target of rapamycin kinase Homo sapiens 91-95 24303008-6 2013 This anorexigenic effect is likely a consequence of decreases in gastric ghrelin secretion induced by the activation of the mTOR/S6K1 intracellular pathway in the stomach following treatment with rimonabant. Rimonabant 196-206 mechanistic target of rapamycin kinase Homo sapiens 124-128 24671870-6 2014 Other promising strategies are inhibition of interleukin 1beta signaling by drugs such as VX-765; modulation of sphingosine 1-phosphate signaling by drugs such as fingolimod; activation of the mammalian target of rapamycin by drugs such as rapamycin; the hormone erythropoietin; and, paradoxically, drugs such as the alpha2 adrenergic receptor antagonist atipamezole and the CB1 cannabinoid antagonist SR141716A (rimonabant) with proexcitatory activity. Rimonabant 402-411 mechanistic target of rapamycin kinase Homo sapiens 193-222 24671870-6 2014 Other promising strategies are inhibition of interleukin 1beta signaling by drugs such as VX-765; modulation of sphingosine 1-phosphate signaling by drugs such as fingolimod; activation of the mammalian target of rapamycin by drugs such as rapamycin; the hormone erythropoietin; and, paradoxically, drugs such as the alpha2 adrenergic receptor antagonist atipamezole and the CB1 cannabinoid antagonist SR141716A (rimonabant) with proexcitatory activity. Rimonabant 413-423 mechanistic target of rapamycin kinase Homo sapiens 193-222