PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24086554-0	2013	Febuxostat, an inhibitor of xanthine oxidase, suppresses lipopolysaccharide-induced MCP-1 production via MAPK phosphatase-1-mediated inactivation of JNK.	Febuxostat	0-10	C-C motif chemokine ligand 2	Homo sapiens	84-89	
24086554-5	2013	Here we show that febuxostat suppresses LPS-induced MCP-1 production and mRNA expression via activating MAPK phosphatase-1 (MKP-1) which, in turn, leads to dephosphorylation and inactivation of JNK in macrophages.	Febuxostat	18-28	C-C motif chemokine ligand 2	Homo sapiens	52-57	
34030558-0	2021	Nephroprotective effects of febuxostat and/or mirtazapine against gentamicin-induced nephrotoxicity through modulation of ERK 1/2, NF-kappaB and MCP1.	Febuxostat	28-38	C-C motif chemokine ligand 2	Homo sapiens	145-149	
34030558-6	2021	RESULTS: Febuxostat and mirtazapine significantly (p<0.05) alleviated biochemical and histopathological alterations that were induced by gentamicin and for the first time, significantly decreased the renal levels of ERK1/2 and MCP-1.	Febuxostat	9-19	C-C motif chemokine ligand 2	Homo sapiens	227-232