PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34194816-6 2021 In this review, we summarise the recent research on neuronal alpha-klotho and discuss how the neuroprotective properties of alpha-klotho could be exploited to tackle age- and neurodegeneration-associated cognitive dysfunction. alpha-klotho 124-136 klotho Homo sapiens 67-73 34721095-0 2021 Reduced Plasma Levels of alpha-Klotho and Their Correlation With Klotho Polymorphisms in Elderly Patients With Major Depressive Disorders. alpha-klotho 25-37 klotho Homo sapiens 65-71 34721095-11 2021 Our data suggest that circulating alpha-Klotho levels combined with Klotho genetic polymorphisms are important in elderly MDD patients, particularly carriers of the Klotho gene rs9315202 T allele. alpha-klotho 34-46 klotho Homo sapiens 165-171 35513125-3 2022 A recent structural analysis revealed that the complex of FGF23 and FGFR1, the physiologic FGF23 receptor in the kidney, includes soluble alpha-klotho (klotho) and heparin, which both act as co-factors for FGF23/FGFR1 signaling. alpha-klotho 138-150 klotho Homo sapiens 152-158