PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27150930-5 2016 Furthermore, we clarified the pharmacological profiles of the acetylcholinesterase inhibitors donepezil, galantamine, and rivastigmine, providing novel insights into their mechanisms of action. Rivastigmine 122-134 acetylcholinesterase Mus musculus 62-82 30521930-6 2019 Single doses of D1R agonists, SKF38393 and SKF82958, and the acetylcholinesterase inhibitor, rivastigmine, alone and the combination of subeffective doses of both DETQ and rivastigmine, also restored NOR in both subchronic PCP-treated in hD1 mice. Rivastigmine 93-105 acetylcholinesterase Mus musculus 61-81 19470293-3 2009 Rivastigmine is an inhibitor of both AChE and butyrylcholinesterase (BChE) whereas donepezil is a selective inhibitor of AChE. Rivastigmine 0-12 acetylcholinesterase Mus musculus 37-41 23026084-3 2012 The three compounds 6a (IC(50)=2.57muM), 6b (IC(50)=0.70 muM) and 6i (IC(50)=2.56 muM) exhibited potent in vitro AChE inhibitory activities comparable to the drug rivastigmine (IC(50)=1.11 muM). Rivastigmine 163-175 acetylcholinesterase Mus musculus 113-117 23026084-5 2012 In addition, the AChE-carbamate Michaelis complexes of these potent compounds including rivastigmine and ganstigmine have been modeled using covalent docking protocol of GOLD and important direct/indirect interactions contributing to stabilization of the AChE-carbamate Michaelis complexes have been investigated. Rivastigmine 88-100 acetylcholinesterase Mus musculus 17-21 23026084-5 2012 In addition, the AChE-carbamate Michaelis complexes of these potent compounds including rivastigmine and ganstigmine have been modeled using covalent docking protocol of GOLD and important direct/indirect interactions contributing to stabilization of the AChE-carbamate Michaelis complexes have been investigated. Rivastigmine 88-100 acetylcholinesterase Mus musculus 255-259 21820013-2 2011 Rivastigmine is a dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE); however, the impact of BuChE inhibition on cognitive dysfunction remains to be determined. Rivastigmine 0-12 acetylcholinesterase Mus musculus 58-62 19470293-6 2009 Infusion of rivastigmine (1 and 10 microM) caused a further doubling of ACh levels in AChE-/- mice within 90-120 min. Rivastigmine 12-24 acetylcholinesterase Mus musculus 86-90 17395211-5 2007 It was found that administration of tacrine, rivastigmine and donepezil in mice significantly attenuated the LPS induced increased levels of IL-2 along with the significant reduction of AChE activity predominantly in salt soluble (SS) fraction as compared to the detergent soluble (DS) fraction in a dose dependent manner. Rivastigmine 45-57 acetylcholinesterase Mus musculus 186-190 15852394-2 2005 We report that peripheral administration of the acetylcholinesterase inhibitors tacrine, rivastigmine, neostigmine, or EN101 (an antisense oligonucleotide directed at acetylcholinesterase messenger RNA) to mice significantly attenuated the production of interleukin-1beta in the hippocampus and blood, concomitantly with the reduction in acetylcholinesterase activity. Rivastigmine 89-101 acetylcholinesterase Mus musculus 48-68 34855998-7 2022 Rivastigmine was found to inhibit AChE whereas HMT and memantine had no effects on AChE or on choline acetyltransferase (ChAT). Rivastigmine 0-12 acetylcholinesterase Mus musculus 34-38 34184291-11 2022 In the in vivo study, test compounds (ACV, Chrysin, and Rivastigmine) improved cognitive impairment, increased the SOD and GSH level, reduced the MDA level and AChE activity, and protected the cortex-hippocampal neurons from degeneration. Rivastigmine 56-68 acetylcholinesterase Mus musculus 160-164 11597825-0 2001 Acetylcholinesterase inhibitor SDZ ENA 713 (Rivastigmine) increases brain pyrrolidone carboxyl peptidase activity. Rivastigmine 31-42 acetylcholinesterase Mus musculus 0-20 11597825-0 2001 Acetylcholinesterase inhibitor SDZ ENA 713 (Rivastigmine) increases brain pyrrolidone carboxyl peptidase activity. Rivastigmine 44-56 acetylcholinesterase Mus musculus 0-20