PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28369189-0 2017 Association of the HLA-B*53:01 Allele With Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS) Syndrome During Treatment of HIV Infection With Raltegravir. Raltegravir Potassium 153-164 major histocompatibility complex, class I, B Homo sapiens 19-24 32766769-1 2021 We present the first published case of raltegravir-associated drug-reaction with eosinophilia and systemic symptoms (DRESS) syndrome in a child without characteristic human leukocyte antigen haplotypes HLA-B*57:01 or HLA-B*53:01. Raltegravir Potassium 39-50 major histocompatibility complex, class I, B Homo sapiens 217-222 21126956-2 2010 METHODS: SHIELD is an ongoing 96-week pilot study of abacavir/lamivudine 600 mg/300 mg once daily with raltegravir 400 mg twice daily among HLA-B*5701-negative adults with screening viral load (VL) > 1,000 copies/mL. Raltegravir Potassium 103-114 major histocompatibility complex, class I, B Homo sapiens 140-145 28369189-9 2017 Conclusions: These data implicate the prevalent African allele HLA-B*53:01 in the immunopathogenesis of raltegravir-induced DRESS syndrome. Raltegravir Potassium 104-115 major histocompatibility complex, class I, B Homo sapiens 63-68 28369189-10 2017 Although the immunopathogenic mechanisms are currently unknown, virtual modeling suggests that raltegravir may bind within the antigen binding cleft of the HLA-B*53:01 molecule, but not within the closely related HLA-B*35:01 molecule. Raltegravir Potassium 95-106 major histocompatibility complex, class I, B Homo sapiens 156-161 28369189-11 2017 Further studies are necessary to confirm the strength of the association between carriage of the HLA-B*53:01 allele and raltegravir-induced DRESS syndrome, and the potential utility of HLA screening before raltegravir treatment. Raltegravir Potassium 120-131 major histocompatibility complex, class I, B Homo sapiens 97-102 24657622-0 2014 Raltegravir and elvitegravir-resistance mutation E92Q affects HLA-B*40:02-restricted HIV-1-specific CTL recognition. Raltegravir Potassium 0-11 major histocompatibility complex, class I, B Homo sapiens 62-67 24657622-3 2014 We here investigated the effect of a raltegravir and elvitegravir-resistance mutation (E92Q) on HLA-B*40:02-restricted Int92-102 (EL11: ETGQETAYFLL)-specific CTLs. Raltegravir Potassium 37-48 major histocompatibility complex, class I, B Homo sapiens 96-101