PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29908090-3 2018 EXPERIMENTAL APPROACH: We identified and analysed mutations in the RET kinase domain that conferred resistance to the TKIs cabozantinib, lenvatinib, vandetanib and nintedanib using RET kinase-dependent BaF3/KIF5B-RET (BaF3/KR) cells. lenvatinib 137-147 kinesin family member 5B Homo sapiens 207-212 23856031-4 2013 In cellular assays, lenvatinib inhibited auto-phosphorylation of KIF5B-RET, CCDC6-RET, and NcoA4-RET. lenvatinib 20-30 kinesin family member 5B Homo sapiens 65-70 25625428-2 2015 Several related clinical trials for non-small-cell lung cancer (NSCLC) with KIF5B-RET rearrangements using existing RET inhibitors, such as lenvatinib, vandetanib, sunitinib, ponatinib, cabozantinib, and AUY922, have been swiftly initiated by the discovery of the KIF5B-RET fusion gene. lenvatinib 140-150 kinesin family member 5B Homo sapiens 76-81