PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33419805-0	2021	Lenvatinib Inhibits AKT/NF-kappaB Signaling and Induces Apoptosis Through Extrinsic/Intrinsic Pathways in Non-small Cell Lung Cancer.	lenvatinib	0-10	nuclear factor kappa B subunit 1	Homo sapiens	24-33	
33419805-6	2021	RESULTS: The cell viability and NF-kappaB activity were suppressed by lenvatinib.	lenvatinib	70-80	nuclear factor kappa B subunit 1	Homo sapiens	32-41	
33419805-9	2021	CONCLUSION: Altogether, lenvatinib induced extrinsic/intrinsic apoptosis and suppressed migration/invasion ability of NSCLC cells that was associated with AKT/NF-kappaB signaling inactivation.	lenvatinib	24-34	nuclear factor kappa B subunit 1	Homo sapiens	159-168	
34864311-0	2022	Revealing the suppressive role of protein kinase C delta and p38 mitogen-activated protein kinase (MAPK)/NF-kappaB axis associates with lenvatinib-inhibited progression in hepatocellular carcinoma in vitro and in vivo.	lenvatinib	136-146	nuclear factor kappa B subunit 1	Homo sapiens	105-114	
34864311-5	2022	Therefore, the primary purpose of the present study was to evaluate the inhibitory effect of lenvatinib and its inhibitory mechanism on the NF-kappaB-mediated progression of HCC in vitro and in vivo.	lenvatinib	93-103	nuclear factor kappa B subunit 1	Homo sapiens	140-149	
34864311-8	2022	An NF-kappaB translocation assay, NF-kappaB reporter gene assay, a Western blotting assay and immunohistochemistry staining were used to investigate the underlying mechanism by which lenvatinib acts on HCC.	lenvatinib	183-193	nuclear factor kappa B subunit 1	Homo sapiens	3-12	
34864311-8	2022	An NF-kappaB translocation assay, NF-kappaB reporter gene assay, a Western blotting assay and immunohistochemistry staining were used to investigate the underlying mechanism by which lenvatinib acts on HCC.	lenvatinib	183-193	nuclear factor kappa B subunit 1	Homo sapiens	34-43	
34864311-10	2022	Lenvatinib may also suppress NF-kappaB translocation and activation.	lenvatinib	0-10	nuclear factor kappa B subunit 1	Homo sapiens	29-38	
34864311-11	2022	We also found both protein kinase C delta (PKC-delta) and p38 mitogen-activated protein kinase (MAPK) inactivation participated in lenvatinib-reduced NF-kappaB signaling.	lenvatinib	131-141	nuclear factor kappa B subunit 1	Homo sapiens	150-159	
34864311-12	2022	In conclusion, this study reveals that the suppression of PKC-delta, and the p38 MAPK/NF-kappaB axis is associated with the lenvatinib-inhibited progression of HCC in vitro and in vivo.	lenvatinib	124-134	nuclear factor kappa B subunit 1	Homo sapiens	86-95