PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9843849-2 1998 NO can combine with superoxide (O-2) to form peroxynitrite, which can decompose into nitrate. Peroxynitrous Acid 45-58 immunoglobulin kappa variable 1D-39 Homo sapiens 32-35 9582295-3 1998 In such studies 3-morpholinosydnonimine N-ethylcarbamide (SIN-1), a compound that simultaneously releases nitric oxide (.NO) and superoxide (O-2), is often used as a source for peroxynitrite. Peroxynitrous Acid 177-190 immunoglobulin kappa variable 1D-39 Homo sapiens 141-144 9582295-11 1998 Likewise, authentic peroxynitrite (1 mM) also induced the formation of both O-2 and H2O2 upon addition to HEPES (400 mM)-containing solutions in a pH (4.5-7.5)-dependent manner. Peroxynitrous Acid 20-33 immunoglobulin kappa variable 1D-39 Homo sapiens 76-79 9006926-9 1997 The second order of reaction for .NO may result from interaction between .NO and O-2 to form peroxynitrite. Peroxynitrous Acid 93-106 immunoglobulin kappa variable 1D-39 Homo sapiens 81-84 23495730-5 2013 These chemicals function in mutation and carcinogenesis and promote inflammation, in which peroxynitrite (a product of O2- and NO) activates MMP, damages DNA and RNA, and regenerates 8-nitroguanosine and 8-oxoguanosine. Peroxynitrous Acid 91-104 immunoglobulin kappa variable 1D-39 Homo sapiens 119-129 9765252-6 1998 However, peroxynitrite formed from .NO and O-2, which were generated at equal rates ( approximately 5 microM x min-1) from 1 mM spermine NONOate, 28 milliunits/ml xanthine oxidase, and 1 mM hypoxanthine was much less efficient (0.67 +/- 0.01 microM; approximately 0.07% of total product flow). Peroxynitrous Acid 9-22 immunoglobulin kappa variable 1D-39 Homo sapiens 43-46