PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32064476-4 2020 Meanwhile, glucose oxidase (GOx) catalyzes glucose hydrolysis to produce hydrogen peroxide (H2O2), which was used to inhibit the formation of Turnbull"s blue by oxidizing iron(ii) to iron(iii). ammonium ferrous sulfate 171-179 hydroxyacid oxidase 1 Homo sapiens 11-26 32064476-4 2020 Meanwhile, glucose oxidase (GOx) catalyzes glucose hydrolysis to produce hydrogen peroxide (H2O2), which was used to inhibit the formation of Turnbull"s blue by oxidizing iron(ii) to iron(iii). ammonium ferrous sulfate 171-179 hydroxyacid oxidase 1 Homo sapiens 28-31 34699188-4 2021 Specifically, hydrogen peroxide, produced in the glucose oxidase (GOx)-catalyzed reaction of d-glucose, accelerated Fe2+ oxidation, and the optimized kinetics profoundly facilitated the film formation to be about 9 times thicker. ammonium ferrous sulfate 116-120 hydroxyacid oxidase 1 Homo sapiens 49-64 30383966-3 2018 Here, an adenosine triphosphate (ATP)-responsive autocatalytic Fenton nanosystem (GOx@ZIF@MPN), incorporated with glucose oxidase (GOx) in zeolitic imidazolate framework (ZIF) and then coated with metal polyphenol network (MPN), was designed and synthesized for tumor ablation with self-supplied H2O2 and TA-mediated acceleration of Fe(III)/Fe(II) conversion. ammonium ferrous sulfate 341-347 hydroxyacid oxidase 1 Homo sapiens 82-85 30383966-3 2018 Here, an adenosine triphosphate (ATP)-responsive autocatalytic Fenton nanosystem (GOx@ZIF@MPN), incorporated with glucose oxidase (GOx) in zeolitic imidazolate framework (ZIF) and then coated with metal polyphenol network (MPN), was designed and synthesized for tumor ablation with self-supplied H2O2 and TA-mediated acceleration of Fe(III)/Fe(II) conversion. ammonium ferrous sulfate 341-347 hydroxyacid oxidase 1 Homo sapiens 114-129 30383966-3 2018 Here, an adenosine triphosphate (ATP)-responsive autocatalytic Fenton nanosystem (GOx@ZIF@MPN), incorporated with glucose oxidase (GOx) in zeolitic imidazolate framework (ZIF) and then coated with metal polyphenol network (MPN), was designed and synthesized for tumor ablation with self-supplied H2O2 and TA-mediated acceleration of Fe(III)/Fe(II) conversion. ammonium ferrous sulfate 341-347 hydroxyacid oxidase 1 Homo sapiens 131-134 30383966-5 2018 Then, GOx reacted with the endogenous glucose to produce plenty of H2O2, and TA reduced Fe(III) to Fe(II), which is a much more vigorous catalyst for the Fenton reaction. ammonium ferrous sulfate 99-105 hydroxyacid oxidase 1 Homo sapiens 6-9 23503321-2 2013 The interfacial initiation system is comprised of an enzymatic reaction between glucose and glucose oxidase (GOx) to generate hydrogen peroxide, which, in the presence of iron (Fe2+), generates hydroxyl radicals that initiate polymerization. ammonium ferrous sulfate 177-181 hydroxyacid oxidase 1 Homo sapiens 92-107 23503321-2 2013 The interfacial initiation system is comprised of an enzymatic reaction between glucose and glucose oxidase (GOx) to generate hydrogen peroxide, which, in the presence of iron (Fe2+), generates hydroxyl radicals that initiate polymerization. ammonium ferrous sulfate 177-181 hydroxyacid oxidase 1 Homo sapiens 109-112 34699188-4 2021 Specifically, hydrogen peroxide, produced in the glucose oxidase (GOx)-catalyzed reaction of d-glucose, accelerated Fe2+ oxidation, and the optimized kinetics profoundly facilitated the film formation to be about 9 times thicker. ammonium ferrous sulfate 116-120 hydroxyacid oxidase 1 Homo sapiens 66-69 34390223-5 2021 An efficient enzymatic/Fenton-starvation nanoreactor PMs loaded with glucose oxidase and perfluoropentane (PGPMs) is constructed through synthesizing methoxy-PEG-carboxymethy-modified iron (Fe2+ /Fe3+ )-based metal-organic frameworks (PMs), followed by loading glucose oxidase (GOx) and perfluoropentane (PFP). ammonium ferrous sulfate 190-194 hydroxyacid oxidase 1 Homo sapiens 69-84 34390223-5 2021 An efficient enzymatic/Fenton-starvation nanoreactor PMs loaded with glucose oxidase and perfluoropentane (PGPMs) is constructed through synthesizing methoxy-PEG-carboxymethy-modified iron (Fe2+ /Fe3+ )-based metal-organic frameworks (PMs), followed by loading glucose oxidase (GOx) and perfluoropentane (PFP). ammonium ferrous sulfate 190-194 hydroxyacid oxidase 1 Homo sapiens 278-281 35379059-7 2022 Next, the substrate H2O2 generated by the reaction between GOx and Glu can be catalyzed by Fe2+ to produce highly cytotoxic OH in situ, which could further kill tumor cells. ammonium ferrous sulfate 91-95 hydroxyacid oxidase 1 Homo sapiens 59-62 33325928-5 2021 Hydroxyl radicals ( OH) were produced for chemodynamic therapy (CDT) employing the Fe2+-driven Fenton reaction, which could be greatly promoted by Fe3+-involved glutathione (GSH) depletion and GOx-catalyzed acidity recovery and H2O2 self-sufficiency. ammonium ferrous sulfate 83-87 hydroxyacid oxidase 1 Homo sapiens 193-196 32537936-3 2020 Here, the prodrug tirapazamine (TPZ)-loaded human serum albumin (HSA)-glucose oxidase (GOx) mixture is prepared and modified with a metal-polyphenol network composed of ferric ions (Fe3+ ) and tannic acid (TA), to obtain a self-amplified nanoreactor termed HSA-GOx-TPZ-Fe3+ -TA (HGTFT) for sustainable and cascade cancer therapy with exogenous H2 O2 production and TA-accelerated Fe3+ /Fe2+ conversion. ammonium ferrous sulfate 386-390 hydroxyacid oxidase 1 Homo sapiens 87-90