PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33325928-5	2021	Hydroxyl radicals ( OH) were produced for chemodynamic therapy (CDT) employing the Fe2+-driven Fenton reaction, which could be greatly promoted by Fe3+-involved glutathione (GSH) depletion and GOx-catalyzed acidity recovery and H2O2 self-sufficiency.	ammonium ferrous sulfate	83-87	hydroxyacid oxidase 1	Homo sapiens	193-196	
34699188-4	2021	Specifically, hydrogen peroxide, produced in the glucose oxidase (GOx)-catalyzed reaction of d-glucose, accelerated Fe2+ oxidation, and the optimized kinetics profoundly facilitated the film formation to be about 9 times thicker.	ammonium ferrous sulfate	116-120	hydroxyacid oxidase 1	Homo sapiens	49-64	
34699188-4	2021	Specifically, hydrogen peroxide, produced in the glucose oxidase (GOx)-catalyzed reaction of d-glucose, accelerated Fe2+ oxidation, and the optimized kinetics profoundly facilitated the film formation to be about 9 times thicker.	ammonium ferrous sulfate	116-120	hydroxyacid oxidase 1	Homo sapiens	66-69	
34390223-5	2021	An efficient enzymatic/Fenton-starvation nanoreactor PMs loaded with glucose oxidase and perfluoropentane (PGPMs) is constructed through synthesizing methoxy-PEG-carboxymethy-modified iron (Fe2+ /Fe3+ )-based metal-organic frameworks (PMs), followed by loading glucose oxidase (GOx) and perfluoropentane (PFP).	ammonium ferrous sulfate	190-194	hydroxyacid oxidase 1	Homo sapiens	69-84	
34390223-5	2021	An efficient enzymatic/Fenton-starvation nanoreactor PMs loaded with glucose oxidase and perfluoropentane (PGPMs) is constructed through synthesizing methoxy-PEG-carboxymethy-modified iron (Fe2+ /Fe3+ )-based metal-organic frameworks (PMs), followed by loading glucose oxidase (GOx) and perfluoropentane (PFP).	ammonium ferrous sulfate	190-194	hydroxyacid oxidase 1	Homo sapiens	278-281	
35379059-7	2022	Next, the substrate H2O2 generated by the reaction between GOx and Glu can be catalyzed by Fe2+ to produce highly cytotoxic  OH in situ, which could further kill tumor cells.	ammonium ferrous sulfate	91-95	hydroxyacid oxidase 1	Homo sapiens	59-62	
32064476-4	2020	Meanwhile, glucose oxidase (GOx) catalyzes glucose hydrolysis to produce hydrogen peroxide (H2O2), which was used to inhibit the formation of Turnbull"s blue by oxidizing iron(ii) to iron(iii).	ammonium ferrous sulfate	171-179	hydroxyacid oxidase 1	Homo sapiens	11-26	
32537936-3	2020	Here, the prodrug tirapazamine (TPZ)-loaded human serum albumin (HSA)-glucose oxidase (GOx) mixture is prepared and modified with a metal-polyphenol network composed of ferric ions (Fe3+ ) and tannic acid (TA), to obtain a self-amplified nanoreactor termed HSA-GOx-TPZ-Fe3+ -TA (HGTFT) for sustainable and cascade cancer therapy with exogenous H2 O2 production and TA-accelerated Fe3+ /Fe2+ conversion.	ammonium ferrous sulfate	386-390	hydroxyacid oxidase 1	Homo sapiens	87-90	
32064476-4	2020	Meanwhile, glucose oxidase (GOx) catalyzes glucose hydrolysis to produce hydrogen peroxide (H2O2), which was used to inhibit the formation of Turnbull"s blue by oxidizing iron(ii) to iron(iii).	ammonium ferrous sulfate	171-179	hydroxyacid oxidase 1	Homo sapiens	28-31	
30383966-3	2018	Here, an adenosine triphosphate (ATP)-responsive autocatalytic Fenton nanosystem (GOx@ZIF@MPN), incorporated with glucose oxidase (GOx) in zeolitic imidazolate framework (ZIF) and then coated with metal polyphenol network (MPN), was designed and synthesized for tumor ablation with self-supplied H2O2 and TA-mediated acceleration of Fe(III)/Fe(II) conversion.	ammonium ferrous sulfate	341-347	hydroxyacid oxidase 1	Homo sapiens	82-85	
30383966-3	2018	Here, an adenosine triphosphate (ATP)-responsive autocatalytic Fenton nanosystem (GOx@ZIF@MPN), incorporated with glucose oxidase (GOx) in zeolitic imidazolate framework (ZIF) and then coated with metal polyphenol network (MPN), was designed and synthesized for tumor ablation with self-supplied H2O2 and TA-mediated acceleration of Fe(III)/Fe(II) conversion.	ammonium ferrous sulfate	341-347	hydroxyacid oxidase 1	Homo sapiens	114-129	
30383966-3	2018	Here, an adenosine triphosphate (ATP)-responsive autocatalytic Fenton nanosystem (GOx@ZIF@MPN), incorporated with glucose oxidase (GOx) in zeolitic imidazolate framework (ZIF) and then coated with metal polyphenol network (MPN), was designed and synthesized for tumor ablation with self-supplied H2O2 and TA-mediated acceleration of Fe(III)/Fe(II) conversion.	ammonium ferrous sulfate	341-347	hydroxyacid oxidase 1	Homo sapiens	131-134	
30383966-5	2018	Then, GOx reacted with the endogenous glucose to produce plenty of H2O2, and TA reduced Fe(III) to Fe(II), which is a much more vigorous catalyst for the Fenton reaction.	ammonium ferrous sulfate	99-105	hydroxyacid oxidase 1	Homo sapiens	6-9	
23503321-2	2013	The interfacial initiation system is comprised of an enzymatic reaction between glucose and glucose oxidase (GOx) to generate hydrogen peroxide, which, in the presence of iron (Fe2+), generates hydroxyl radicals that initiate polymerization.	ammonium ferrous sulfate	177-181	hydroxyacid oxidase 1	Homo sapiens	92-107	
23503321-2	2013	The interfacial initiation system is comprised of an enzymatic reaction between glucose and glucose oxidase (GOx) to generate hydrogen peroxide, which, in the presence of iron (Fe2+), generates hydroxyl radicals that initiate polymerization.	ammonium ferrous sulfate	177-181	hydroxyacid oxidase 1	Homo sapiens	109-112