PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1951574-9 1991 The triazole antifungals, terconazole and itraconazole, combine a high affinity for Candida P-45014DM with an exceptionally low effect on mammalian cytochrome P-450. terconazole 26-37 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 148-164 2677363-7 1989 Terconazole has far greater selectively for yeast cytochrome P-450 than for mammalian microsomal cytochrome P-450. terconazole 0-11 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 97-113 2677363-4 1989 The basic mechanism of action of terconazole, inhibition of fungal cytochrome P-450, is similar to that of the imidazoles. terconazole 33-44 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 67-83 2677363-5 1989 However, because of the additional nitrogen atom in the triazole ring and the lipophilic tail, terconazole establishes a firmer and longer-lasting link with the membrane-bound fungal cytochrome P-450. terconazole 95-106 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 183-199 2677363-7 1989 Terconazole has far greater selectively for yeast cytochrome P-450 than for mammalian microsomal cytochrome P-450. terconazole 0-11 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 50-66 2677363-10 1989 The high affinity and selectivity of terconazole for fungal cytochrome P-450 and its potent in vitro and in vivo activity indicate that the drug may well become a significant agent for the treatment of fungal disease. terconazole 37-48 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 60-76