PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29923216-8 2018 Furthermore, the migrative and invasive capabilities of renal cancer cells were markedly repressed by BA treatment, which was related to upregulation of matrix metalloproteinase (MMP)2, MMP9, and vimentin, and downregulation of tissue inhibitor of metalloproteinase 2 and E-cadherin. betulinic acid 102-104 matrix metallopeptidase 9 Homo sapiens 186-190 29423083-6 2018 Furthermore, histological and immunohistochemical analyses showed a decrease in MMP-9 positive cells, MMP-2 positive cells and Ki-67 positive cells and an increase in cleaved caspase-3 positive cells upon BA administration. betulinic acid 205-207 matrix metallopeptidase 9 Homo sapiens 80-85 30417527-8 2019 Furthermore, BA also significantly inhibited HCC growth in vivo and blocked pulmonary metastasis of HCC by regulating the metastasis-related proteins including MMP-2, MMP-9, and TIMP2 without obvious toxicity. betulinic acid 13-15 matrix metallopeptidase 9 Homo sapiens 167-172 20872792-11 2010 Our results showed that BA exerts multiple effects on HG-induced HASMC proliferation and migration, including the inhibition of both MMP-2 and MMP-9 transcription, protein activity, and the downregulation of ROS/NF-kappaB signaling, thereby suggesting that BA may be a possible therapeutic approach to the inhibition of diabetic vascular disease. betulinic acid 24-26 matrix metallopeptidase 9 Homo sapiens 143-148 33806566-10 2021 Furthermore, we found that BA suppressed the wound healing and invasion ability, and decreased the expression of Snail and Slug in T24 and 5637 cells, and matrix metalloproteinase (MMP)-9 in UMUC-3 cells. betulinic acid 27-29 matrix metallopeptidase 9 Homo sapiens 155-187