PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24274355-9	2014	Using the P-gp inhibitor zosuquidar, P-gp mediated excretion of darunavir from blood towards gastrointestinal lumen was evidenced and this was confirmed by transport studies in Caco-2 cells.	Darunavir	64-73	phosphoglycolate phosphatase	Rattus norvegicus	10-14	
24274355-10	2014	Moreover, involvement of P-gp in the biliary excretion of darunavir was also demonstrated in situ.	Darunavir	58-67	phosphoglycolate phosphatase	Rattus norvegicus	25-29	
23395914-2	2013	To evaluate to what extent the regional differences in expression of P-gp and P450 enzymes affect the absorption of a dual substrate, we investigated the transport of darunavir across different small intestinal segments (duodenum, proximal jejunum and ileum).	Darunavir	167-176	phosphoglycolate phosphatase	Rattus norvegicus	69-82	
23395914-5	2013	The involvement of P-gp in the absorption of darunavir was clearly shown by coperfusion of darunavir with the P-gp inhibitor zosuquidar.	Darunavir	45-54	phosphoglycolate phosphatase	Rattus norvegicus	19-23	
23395914-5	2013	The involvement of P-gp in the absorption of darunavir was clearly shown by coperfusion of darunavir with the P-gp inhibitor zosuquidar.	Darunavir	45-54	phosphoglycolate phosphatase	Rattus norvegicus	110-114	
23395914-5	2013	The involvement of P-gp in the absorption of darunavir was clearly shown by coperfusion of darunavir with the P-gp inhibitor zosuquidar.	Darunavir	91-100	phosphoglycolate phosphatase	Rattus norvegicus	19-23	
23395914-5	2013	The involvement of P-gp in the absorption of darunavir was clearly shown by coperfusion of darunavir with the P-gp inhibitor zosuquidar.	Darunavir	91-100	phosphoglycolate phosphatase	Rattus norvegicus	110-114	
23395914-8	2013	Upon studying the drug-drug interaction of darunavir with ketoconazole, data were indicative for an inhibitory effect of ketoconazole on P-gp as the main mechanism for the increased transport of darunavir across the small intestine.	Darunavir	43-52	phosphoglycolate phosphatase	Rattus norvegicus	137-141	
23395914-8	2013	Upon studying the drug-drug interaction of darunavir with ketoconazole, data were indicative for an inhibitory effect of ketoconazole on P-gp as the main mechanism for the increased transport of darunavir across the small intestine.	Darunavir	195-204	phosphoglycolate phosphatase	Rattus norvegicus	137-141