PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35319278-4 2022 These mutated residues changed the flexibility of the flap region in PR, and thus affected its binding energy with DRV and CA-p2, resulting in differences in sensitivity. Darunavir 115-118 cyclase associated actin cytoskeleton regulatory protein 2 Homo sapiens 123-128