PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16687414-4 2006 Overexpression of dominant negative PKCdelta or pretreatment with a PKCdelta inhibitor (rottlerin) or Src kinase family inhibitor (PP2) partially blocked LPA-induced MMP activation, proHB-EGF shedding, and EGFR tyrosine phosphorylation. rottlerin 88-97 epidermal growth factor receptor Homo sapiens 206-210 32125625-3 2020 We found that incubating astrocytes with bisindolylmaleimide (BIM, an inhibitor of classical and novel PKC isoforms) or rottlerin, a PKCdelta-specific inhibitor, attenuated the ammonia-induced phosphorylation of EGFR, while GF109203X had no effect on this pathway. rottlerin 120-129 epidermal growth factor receptor Homo sapiens 212-216 21127066-10 2011 Extracellular HSP90alpha induced EGFR phosphorylation at Tyr-1068, and this event was prevented by both the protein kinase Cdelta inhibitor, rottlerin, and the c-Src inhibitor, PP2. rottlerin 141-150 epidermal growth factor receptor Homo sapiens 33-37 15177934-8 2004 The effects of NT on EGFR/ERK/Akt activation and DNA synthesis were attenuated by PLC-inhibitor (U73122), PKC-inhibitors (bisindolylmaleimide, staurosporine, rottlerin), MEK inhibitor (U0126) and PI3 kinase inhibitors (wortmannin, LY 294002). rottlerin 158-167 epidermal growth factor receptor Homo sapiens 21-25 15618223-5 2005 PMA-induced phosphorylation of the EGFR at Tyr(1068) was blocked by bisindolylmaleimide (BIM), a PKC inhibitor, and rottlerin, a PKCdelta-specific inhibitor. rottlerin 116-125 epidermal growth factor receptor Homo sapiens 35-39 15342779-3 2004 Analysis of PKC isoforms reveals that inhibition of PKCdelta with rottlerin or its down-modulation by using small interfering RNA is specifically responsible for the release of the W13 blockage of EGFR trafficking from early endosomes. rottlerin 66-75 epidermal growth factor receptor Homo sapiens 197-201