PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11120819-3 2000 Signaling via both the TCR and CD28 is required for optimal activation of the multisubunit IkappaB kinase (IKK) complex in primary human T lymphocytes; this activation could be inhibited by a Ca(2+)-independent PKC isoform inhibitor, rottlerin. rottlerin 234-243 protein kinase C theta Homo sapiens 211-214 26862528-6 2016 A phospholipase C inhibitor (U73122) partially blunt- ed the induction of IL-10 mRNA expression by HNE, while IL-10 mRNA expression was significantly reduced by a protein kinase C (PKC) inhibitor (Rottlerin). rottlerin 197-206 protein kinase C theta Homo sapiens 181-184 17141738-1 2007 Rottlerin is a pharmacological inhibitor of protein kinase C (PKC) theta, a novel PKC selectively expressed in T lymphocytes. rottlerin 0-9 protein kinase C theta Homo sapiens 44-72 17141738-1 2007 Rottlerin is a pharmacological inhibitor of protein kinase C (PKC) theta, a novel PKC selectively expressed in T lymphocytes. rottlerin 0-9 protein kinase C theta Homo sapiens 62-65 22330070-10 2012 We also showed that inhibition of PKCtheta by rottlerin or dominant negative PKCtheta reduced AMPK-mediated transcriptional activation of NF-AT and AP-1 in activated Jurkat cells. rottlerin 46-55 protein kinase C theta Homo sapiens 34-42