PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12525155-6 2003 In membranes, inhibition of PKCdelta by rottlerin enhanced BK activation of PLD but inhibited that by S1P. rottlerin 40-49 glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens 76-79 12525155-7 2003 Rottlerin inhibited activation of PLD in nuclei by both BK and S1P. rottlerin 0-9 glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens 34-37 11419696-7 2001 Furthermore, rottlerin and Go 6976, the PKC inhibitors specific for PKC-delta, -alpha and -betaI, respectively, markedly inhibited the PLD activity stimulated by BK. rottlerin 13-22 glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens 135-138 17130901-0 2007 Rottlerin inhibits P2X(7) receptor-stimulated phospholipase D activity in chronic lymphocytic leukaemia B-lymphocytes. rottlerin 0-9 glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens 46-61 17130901-3 2007 Rottlerin, an inhibitor of novel protein kinase C (PKC) isoforms, but not GF 109203X, an inhibitor of conventional PKC isoforms, impaired the ATP-stimulated PLD activity in CLL B-lymphocytes. rottlerin 0-9 glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens 157-160 17130901-5 2007 The inhibition of P2X(7)-stimulated PLD activity by rottlerin was attributed to a target downstream of P2X(7) activation, as the ATP-mediated (86)Rb(+) efflux from CLL B-lymphocytes was not altered in the presence of rottlerin. rottlerin 52-61 glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens 36-39 17130901-5 2007 The inhibition of P2X(7)-stimulated PLD activity by rottlerin was attributed to a target downstream of P2X(7) activation, as the ATP-mediated (86)Rb(+) efflux from CLL B-lymphocytes was not altered in the presence of rottlerin. rottlerin 217-226 glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens 36-39 11749856-7 2001 Pretreatment of cells with PKC inhibitors Ro-31-8220, staurosporine, and rottlerin increased the propranolol-induced PLD. rottlerin 73-82 glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens 117-120